MELATONINA
-Antiage
-Antiox (Riduce l’ossidazione e i danni dovuti ai radicali liberi)
-Antistress (benefica per il rapporto Cortisolo/Testosterone)
-Miorilassante-Immunostimolante (Rafforza il Sistema Immunitario)
-Anticancerogeno (Inibisce lo sviluppo e/o la crescita di diverse linee tumorali e favorendone l’apoptosi)
-Migliora le Performances Sessuali
-Previene la depressione
-Migliora significativamente l’attività della tiroide
-Riduce la replicazione del virus HIV -Valido aiuto nei periodi di Pre Mestruazioni ed Ovulazione femminili Dermatoendocrinol. 2012 Jul 1; 4(3): 245–252.Melatonin and human skin agingKonrad Kleszczynski and Tobias W. Fischer
Melatonin can slow down the effects of aging. A team at laboratoire Arago in Banyuls sur Mer (CNRS / Université Pierre et Marie Curie) Ganie SA, Dar TA, Bhat AH, et al. Melatonin: A Potential Anti-Oxidant Therapeutic Agent for Mitochondrial Dysfunctions and Related Disorders. Rejuvenation Res. 2016;19(1):21-40.
MAESTRONI, G.J.M., A. CONTI, W. PIERPAOLI (1986) Role of the pineal gland in immunity. Circadian synthesis and release of melatonin modulates the antibody response and antagonizes the immunosuppressive effect of corticosterone. J. Neuroimmunol. 13:1!30. DELGOBBO, V., V. LIBRI, N. VILLANI, R. CALIO, G. NISTICO (1989) Pinealectomy inhibits interleukin-2 production and natural killer activity in mice. Int. J. Immunopharacol. 11: MAESTRONI, G.J.M., A. CONTI, W. PIERPAOLI (1989) Melatonin, stress, and the immune system. In: Pineal Research Reviews, Vol. 7. R.J. Reiter, ed. Alan R. Liss, New York MedGenMed Neurology & Neurosurgery
The Therapeutic Potential of Melatonin: A Review of the Science
Samir Malhotra, MD; Girish Sawhney, MD; Promila Pandhi, MD
Immunol Lett. 1987 Dec;16(3-4):355-61. Melatonin: a principal neuroimmunoregulatory and anti-stress hormone: its anti-aging effects.Pierpaoli W,Maestroni GJ. Int J Mol Sci. 2017 Apr; 18(4): 843.Melatonin, a Full Service Anti-Cancer Agent: Inhibition of Initiation, Progression and MetastasisRussel J. Reiter,Sergio A. Rosales-Corral,Dun-Xian Tan,Dario Acuna-Castroviejo,Lilan Qin,Shun-Fa Yang,and Kexin Xu Oncotarget. 2017 Jun 13; 8(24): 39896–39921.Melatonin for the prevention and treatment of cancerYa Li,Sha Li,Yue Zhou,Xiao Meng,Jiao-Jiao Zhang,Dong-Ping Xu, and Hua-Bin Li Int J Mol Sci. 2013 Feb; 14(2): 2410–2430.Melatonin Anticancer Effects: ReviewGiuseppe Di Bella,Fabrizio Mascia,Luciano Gualano,and Luigi Di Bella Hevia D, Gonzalez-Menendez P, Quiros-Gonzalez I, et al. Melatonin uptake through glucose transporters: a new target for melatonin inhibition of cancer. J Pineal Res. 2015;58(2):234-50. Anisimov VN, Popovich IG, Zabezhinski MA, et al. Melatonin as antioxidant, geroprotector and anticarcinogen. Biochim Biophys Acta. 2006;1757(5-6): 573-89. Jenwitheesuk A, Nopparat C, Mukda S, et al. Melatonin regulates aging and neurodegeneration through energy metabolism, epigenetics, autophagy and circadian rhythm pathways. Int J Mol Sci.2014;15(9):16848-84. Cardinali DP, Pagano ES, Scacchi Bernasconi PA, et al. Melatonin and mitochondrial dysfunction in the central nervous system. Horm Behav. 2013;63(2):322-30. Brain Res. 2000 Sep 29;878(1-2):98-104.
Acute low doses of melatonin restore full sexual activity in impotent male rats.
The effect of melatonin on the sexual function among postmenopausal women: A randomized placebo-controlled trial
Nehle Parandavar, Khadijeh Abdali, Sara Keshtgar, Masoumeh Emamghoreishi, Seddegheh Amooee, Leili Mosalanejad
Research Center for Social Determinants of Health, Jahrom University of Medical Sciences, Jahrom, Iran Department of Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran Department of Physiology, Shiraz University of Medical Sciences, Shiraz, Iran Department of Pharmacology, Shiraz University of Medical Sciences, Shiraz, Iran Department of Obstetrics and Gynecology, Shiraz University of Medical Sciences, Shiraz, Iran
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